Hyperbaric oxygen for treatment of long COVID-19 syndrome (HOT-LoCO): protocol for a randomised, placebo-controlled, double-blind, phase II clinical trialArticle Published on 2022-11-022022-11-15 Journal: BMJ Open [Category] SARS, 진단, [키워드] approved assessment baseline Blood Cardiology case sery chronic fatigue syndrome chronic inflammation clinical clinical trial cognitive collected common COVID-19 defined domain double-blind dysfunction Effect effective Efficacy endothelial function Ethics evaluate fatigue healthy subject hyperbaric oxygen hypothese immunology IMPROVE Inconclusive independent individual initial institutional review board Long malaise mechanism monitoring board oxygen Oxygen therapy pandemic Patient peer-reviewed performed physical placebo-controlled placebo-controlled clinical trial positive Potential treatment product protocol Quality of life Questionnaires randomised rehabilitation medicine respiratory medicine (see thoracic medicine) secondary endpoint suggested survey Swedish Symptom syndrome the primary endpoint Treatment Trial VASCULAR MEDICINE. [DOI] 10.1136/bmjopen-2022-061870 PMC 바로가기
Central Retinal Vein Occlusion After Discontinuation of Rivaroxaban Therapy in a Young Patient with COVID-19 Pulmonary Embolism: A Case ReportArticle Published on 2022-11-012022-11-15 Journal: The American journal of case reports [Category] 진단, [키워드] anticoagulation Combination common contributing to Convalescent plasma therapy Course COVID-19 decrease Dexamethasone diagnosed discharge edema Factor healthy Hospitalized hypercoagulability initiated intravitreal injection knowledge occurred Oxygen therapy Patient Prophylactic pulmonary rebound Remdesivir report retinal vein retinal vein occlusion rivaroxaban Severe COVID-19 pneumonia significantly subsegmental the patient therapeutic therapy treated Treatment visual acuity was performed were excluded with COVID-19 [DOI] 10.12659/AJCR.937739 PMC 바로가기
Dedicated team to ambulatory care for patients with COVID-19 requiring oxygen: Low rate of hospital readmissionResearch article Published on 2022-10-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 치료기술, [키워드] anticoagulation Care consensual COVID-19 determine ED physician emergency department Focusing hospital less Medical organization objective outcome oxygen Oxygen requirement Oxygen therapy Patient patients with COVID-19 Pneumonia prescription readmission Result selected steroid Treatment treatment for COVID-19 [DOI] 10.1016/j.ijid.2022.07.057 [Article Type] Research article
Six-month humoral and cellular immune response to the third dose of BNT162b2 anti-SARS-CoV-2 vaccine in patients with solid tumors: a longitudinal cohort study with a focus on the variants of concernArticle Published on 2022-10-012022-11-15 Journal: ESMO open [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] anti-SARS-CoV-2 Anti-spike antibody BNT162b2 BNT162b2 anti-SARS-CoV-2 vaccine BNT162b2 vaccine booster Cancer cancer patient cell-mediated immune Cellular immune response Concentration COVID-19 delta variant dose evaluated follow-up period highest highlight Hospitalization humoral Immunoglobulin Infection interferon-γ interquartile range longitudinal cohort study lowest median Messenger RNA Neutralizing Neutralizing activity neutralizing antibody of BNT162b2 omicron Oxygen therapy Patient positive response reduced reduction in required SARS-CoV-2 serum Seven solid tumor subject the SARS-CoV-2 third dose. Treatment triggering Vaccine variant variants of concern VOCs were measured were used whole blood sample wild-type strain [DOI] 10.1016/j.esmoop.2022.100574 PMC 바로가기
Targeted therapy in Coronavirus disease 2019 (COVID-19): Implication from cell and gene therapy to immunotherapy and vaccineReview article Published on 2022-10-012022-10-05 Journal: International immunopharmacology [Category] COVID19(2023년), SARS, 변종, 임상, 치료제, [키워드] acute respiratory syndrome affected antiviral agent approach approved caused Cell Cell based therapy characterized coronavirus coronavirus 2 Coronavirus disease 2019 Corticosteroids COVID-19 drug evaluated Gene therapy high risk highly pathogenic immune Immunotherapy in vitro in vivo Inflammatory Medical conditions modulating outcomes Oxygen therapy Patient Population SARS-CoV-2 syndrome targeted therapy therapeutic option therapy thrombosis Treatment Vaccine variety Vascular injury virus [DOI] 10.1016/j.intimp.2022.109161 [Article Type] Review article
Early report on the severity of COVID-19 in hematologic patients infected with the SARS-CoV2 omicron variantArticle Published on 2022-10-012022-11-16 Journal: European journal of haematology [Category] COVID19(2023년), SARS, 변종, [키워드] Ageusia Asymptomatic cause caused condition cough COVID-19 Critical death described disease disease severity fatigue Fever hematologic Hematologic diseases heterogeneous high risk host immunity ICU admission immunodeficiency Infection investigated laboratory parameter less majority Mild symptom morbidity and mortality Mortality nucleic acid amplification observation period occurred Omicron variant Omicron. Oxygen therapy Patient patient cohort patients remained reported reported symptom required SARS-CoV2 SARS-CoV2 infection severity severity of COVID-19 symptoms of COVID-19 variants viral pathogenicity [DOI] 10.1111/ejh.13818 PMC 바로가기
A tendency to worse course of multisystem inflammatory syndrome in children with obesity: MultiOrgan Inflammatory Syndromes COVID-19 related studyArticle Published on 2022-09-262022-11-15 Journal: Frontiers in Endocrinology [Category] 진단, [키워드] Abnormalities Analysis available data BMI body mass index childhood Childhood obesity children collected Comorbidity Course COVID-19 COVID-19 infection COVID-19 severity criteria discharge disease entity duration of symptom form Frequency higher risk Hospitalization Inflammatory intensive care Intravenous immunoglobulin MIS-C National no difference obese obesity obesity. Odds ratio Oxygen therapy participant pathophysiology Patient patients patients with obesity PIMS Poland populations pro-inflammatory recruited risk factor syndrome Treatment worsening [DOI] 10.3389/fendo.2022.934373 PMC 바로가기
Management of dermatomyositis patients amidst the COVID-19 pandemic: Two case reportsArticle Published on 2022-09-232022-11-15 Journal: Medicine [Category] SARS, 치료제, [키워드] Anti-inflammatory therapy anti-inflammatory treatment anticoagulation Antiviral treatment Case report Characteristics Chest China coronavirus coronavirus disease cough COVID-19 COVID-19 infection dermatomyositis diagnosed diagnosed with COVID-19 Diagnosis discharged Diseases effective Epidemic Fever glucocorticoid Increased infected with COVID-19 Interstitial lung disease laboratory result male management negative PCR test Oxygen therapy pathogenic Patient patients with COVID-19 plasma Prophylactic real-time reverse-transcriptase polymerase-chain-reaction repeated RT-PCR SARS-CoV-2 Shortness of breath Spread Symptom the SARS-CoV-2 virus therapy Treatment Wuhan [DOI] 10.1097/MD.0000000000030634 PMC 바로가기
Clinical efficacy of casirivimab-imdevimab antibody combination treatment in patients with COVID-19 Delta variant코로나19 델타 변이형 환자에서 카시리비맙-임데비맙 항체 병용요법의 임상적 효능Article Published on 2022-09-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 변종, 임상, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus 2 administration age antibody cocktail antibody combination antibody treatment Casirivimab Casirivimab-imdevimab treatment clinical Clinical efficacy cocktail Combination conducted control group coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient death Delta delta variant dose Efficacy evaluate FIVE High flow nasal cannula high-risk patient High-risk patients hospital Hospitalization Imdevimab inclusion criteria intravenously Japan mechanical ventilation monoclonal antibodies monoclonal antibody nasal nasal cannula Neutralizing antibodies outcome oxygen Oxygen therapy Patient patients with COVID-19 receive reduce reduced respiratory risk SARS-CoV-2 SARS-CoV-2. significantly lower therapy Treatment treatment group Viral Viral load with COVID-19 [DOI] 10.1016/j.jiac.2022.05.012 PMC 바로가기 [Article Type] Article
COVID-19-associated Mucormycosis: A clinico-epidemiological studyObservational Study Published on 2022-09-012022-10-05 Journal: Journal of diabetes and its complications [Category] SARS, 임상, [키워드] Admission age alkaline phosphatase Antibiotics Antifungal treatment Blood Group Chronic kidney disease COVID-19 COVID-19 illness death diabetes diagnosed disease eight enrolled epidemiological expected Follow-up Frequency hyperglycemia increase in India Ivermectin Mortality much lower Mucormycosis occurred Oxygen therapy pandemic Patient patients died Pneumonia Posaconazole positive raised required risk factor RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RT-PCR serology serum creatinine significantly steroid Steroids survived the patient Treatment uncontrolled use of antibiotics ventilator was done Zinc zinc supplementation zinc. [DOI] 10.1016/j.jdiacomp.2022.108284 PMC 바로가기 [Article Type] Observational Study